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Synthesis of Novel 1,2,4‐oxadiazoline Derivatives Containing Quinoline Moiety by 1,3‐Dipolar Cycloaddition
Author(s) -
Huang Le,
Fei TingHong,
Hu Kun,
Liu FangMing
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2126
Subject(s) - chemistry , cycloaddition , quinoline , moiety , 1,3 dipolar cycloaddition , elemental analysis , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , catalysis
A series of novel 1,2,4‐oxadiazoline derivatives containing 2‐(1,2,4‐triazol‐1‐yl)quinoline were synthesized by the reaction of imines with benzohydroximinoyl chlorides in the presence of Et 3 N via 1,3‐diplolar cycloaddition reaction . The structures of the target compounds were confirmed by IR, 1 H NMR, MS, elemental, and X‐ray crystallographic analysis.