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A novel and efficient method for the synthesis of 5‐arylnaphtho[2,1‐ c ][2,7]naphthyridine derivatives catalyzed by iodine
Author(s) -
Wang XiangShan,
Li Qing,
Wu JianRong,
Yao ChangSheng,
Tu ShuJiang
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.212
Subject(s) - chemistry , iodine , yield (engineering) , aldehyde , catalysis , amine gas treating , combinatorial chemistry , reaction conditions , simplicity , organic chemistry , philosophy , materials science , epistemology , metallurgy
A novel method for the synthesis of 1,2‐dihydro‐5‐arylnaphtho[2,1‐ c ][2,7]naphthyridine derivatives via a three‐component reaction of aromatic aldehyde, naphthalen‐2‐amine, and N ‐substituted piperidin‐4‐one derivatives is described using 5 mol % iodine as catalyst. The features of this new procedure are mild reaction condition, high yield, operational simplicity, and uses available reactants. J. Heterocyclic Chem., (2009).

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