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A green and efficient synthesis of 3,3′‐arylidenebis[4‐hydroxy‐6‐methyl‐2(1 H )‐3‐pyridinone]s in water under microwave irradiation
Author(s) -
Shi Feng,
Cao Longji,
Ma Ning,
Zhang Ge,
Chen Rongshun,
Zhang Yajie,
Tu Shujiang
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.210
Subject(s) - chemistry , microwave irradiation , ammonium acetate , pyran , microwave , organic chemistry , green chemistry , nuclear chemistry , catalysis , reaction mechanism , high performance liquid chromatography , physics , quantum mechanics
AbstractA series of 3,3′‐arylidenebis[4‐hydroxy‐6‐methyl‐2(1 H )‐3‐pyridinone]s were synthesized via three‐component reactions of aromatic aldehydes, 4‐hydroxy‐6‐methyl‐2 H ‐pyran‐2‐one, and ammonium acetate in water under microwave irradiation. This method has the advantages of environmental friendliness, short reaction time, high yields, and easy operation. This efficient synthesis not only offers an economical and green synthetic strategy to this class of significant compounds but also enriches the investigations on microwave‐assisted synthesis in water. J. Heterocyclic Chem., (2010).