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Design, Synthesis and Antimicrobial Evaluation of Novel Tricyclic Benzoxazine Fluoroquinolones under Conventional and Microwave Methods
Author(s) -
Guruswamy B.,
Arul R.,
Chaitanya M. V. S. R. K.,
Darsi S. S. Praveen Kumar
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2093
Subject(s) - antimicrobial , chemistry , tricyclic , imidazole , microwave irradiation , combinatorial chemistry , microwave , organic chemistry , catalysis , physics , quantum mechanics
In view of obtaining some potential antimicrobial compounds, we have described synthesis of novel fluoroquinolones bearing 2‐(piperidin‐4‐yl)‐1 H ‐benzo[ d ]imidazole and evaluated for their antimicrobial activity . Alternatively, synthesis of these products was also demonstrated using microwave irradiation technique. The antimicrobial activity of newly synthesized compounds was evaluated against number of microorganisms and the activity is compared with highly active levofloxacin.