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P( n ‐Bu) 3 Catalyzed Reactions of Salicyl N ‐Thiophosphinyl Imines with Allenylphosphonates: Synthesis of Phosphono‐Chromans
Author(s) -
Rama Suresh R.,
Prasad Tulichala R. N.,
Kotikalapudi Ramesh,
Kumara Swamy K. C.
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2071
Subject(s) - chemistry , phosphine , catalysis , phosphorus , medicinal chemistry , stereochemistry , organic chemistry
A phosphine [P( n ‐Bu) 3 ]‐catalyzed reaction for the synthesis of phosphono‐chromans from allenylphosphonates and salicyl N ‐thiophosphinyl imines has been described and compared with reactions for phosphorus‐free allenes. The products are (β,γ)‐cyclized and are obtained in good yields (57–83%). A key product is characterized by X‐ray crystallography.