Feasible Approach to Tricyclic and Tetracyclic cyclododecanone | Zendy

Zoorob Hanafi H. | Zendy; Elsherbini Mohamed S. | Zendy; Hamama Wafaa S. | Zendy

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Feasible Approach to Tricyclic and Tetracyclic cyclododecanone

Author(s) -

Zoorob Hanafi H.,

Elsherbini Mohamed S.,

Hamama Wafaa S.

Publication year - 2016

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.2062

Subject(s) - chemistry , thiophenol , thiazole , benzimidazole , tricyclic , ring (chemistry) , stereochemistry , derivative (finance) , furan , thiol , organic chemistry , combinatorial chemistry , financial economics , economics

2‐Bromocyclododecanone was utilized as precursor to synthesize polyfused heterocyclic cyclododecane ring systems. Transformation of 2‐bromocyclododecanone ( 5 ) with 1 H ‐benzimidazole‐2‐thiole ( 6 ), benzo[ d ]thiazole‐2‐thiol ( 9 ), 2 ‐naphthol ( 12 ), and thiophenol ( 15 ) afforded thiazolo[2,3‐b]benzimidazole ( 8 ), thiazolo[2,3‐b]benzothaizole derivative ( 11 ) naphtho[1,2‐d]furan derivative ( 14 ) and 2‐(phenylthio)cyclododecanone ( 16 ), respectively.

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