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An efficient procedure for the synthesis of substituted pyridines using KF·Al 2 O 3
Author(s) -
Das Biswanath,
Ravikanth Bommena,
Kumar Avula Satya,
Kanth Boddu Shashi
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.206
Subject(s) - chemistry , malononitrile , potassium fluoride , catalysis , potassium , fluoride , component (thermodynamics) , organic chemistry , combinatorial chemistry , medicinal chemistry , inorganic chemistry , thermodynamics , physics
Three‐component coupling of aldehydes, malononitrile, and thiophenols has efficiently been carried out at room temperature using potassium fluoride on alumina (KF·Al 2 O 3 ) as a catalyst to furnish highly substituted pyridines in high yields. J. Heterocyclic Chem., (2009).