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Synthesis of New 1, 10‐Phenanthroline Analogs as Potent Antimicrobial Agents Using Montmorillonite K‐10 as Catalyst
Author(s) -
Pagadala Ramakanth,
Chidurala Praveen,
Jetti Venkateshwarlu,
Meshram Jyotsna S.,
Maddila Suresh,
Jonnalagadda Sreekanth B.
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.2058
Subject(s) - chemistry , montmorillonite , ethyl acetoacetate , ammonium acetate , catalysis , quinoline , phenanthroline , antimicrobial , organic chemistry , domino , nuclear chemistry , medicinal chemistry , high performance liquid chromatography
A series of new 1, 10‐phenanthroline derivatives are synthesized by the four‐component domino reactions of 8‐hydroxy quinoline, aromatic aldehydes, methyl/ethyl acetoacetate and ammonium acetate in the presence of zeolite (montmorillonite K‐10) using both conventional and microwave methods. Most of the new compounds possessed moderate to significant anti‐bacterial and anti‐fungal activities.