Premium
Synthesis of Dithiocarbamates Containing Disulfide Linkage Using Cyclic Trithiocarbonate and Amines under Solvent–Catalyst Free Condition
Author(s) -
Lal Nand,
Sarswat Amit,
Kumar Lalit,
Nandikonda Karthik,
Jangir Santosh,
Bala Veenu,
Sharma Vishnu Lal
Publication year - 2015
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1995
Subject(s) - chemistry , dithiocarbamate , catalysis , carbon disulfide , disulfide bond , solvent , organic chemistry , biochemistry
A green and facile synthesis of dithiocarbamate derivatives containing disulfide linkage by the ring opening reaction of trithiocarbonate with amines under solvent and catalyst‐free condition with excellent yields is being reported. Environmental benignity, easy work up, smaller reaction time, and lack of column chromatography are the significant features of this protocol. The cyclic trithiocarbonate ( 1 ) has been used as a starting material for the first time to synthesize compounds of biological interest ( 3a , 3b , 3c , 3d , 3e , 3f , 3g , 3h , 3i , 3j , 3k , 3l , 3m , 3n , 3o , 3p , 3q ).