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Novel Synthesis of 6‐Substituted 2‐Picolines from Aryl/heteroaryl β‐Enaminones and Meldrum's Acid Using CeCl 3 .7H 2 O/NaI
Author(s) -
Addla Dinesh,
Kantevari Srinivas
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1941
Subject(s) - chemistry , meldrum's acid , ammonium acetate , tandem , aryl , regioselectivity , condensation , combinatorial chemistry , ammonium , medicinal chemistry , stereochemistry , organic chemistry , catalysis , materials science , high performance liquid chromatography , alkyl , composite material , physics , thermodynamics
One‐pot condensation of aryl/heteroaryl β‐enaminones, Meldrum's acid, and ammonium acetate in the presence of CeCl 3 .7H 2 O/NaI via tandem Michael addition–cyclodehydration–elimination sequence led to the formation of novel regioselective 6‐substituted 2‐picolines.
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