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One‐pot synthesis of polyfunctionalized pyrans catalyzed by basic ionic liquid in aqueous media
Author(s) -
Gong Kai,
Wang HuaLan,
Luo Jun,
Liu ZuLiang
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.193
Subject(s) - chemistry , dimedone , malononitrile , ionic liquid , catalysis , methylene , aqueous medium , organic chemistry , condensation , aqueous solution , condensation reaction , green chemistry , one pot synthesis , phenols , physics , thermodynamics
An efficient and convenient method for the synthesis of polyfunctionalized 4 H ‐pyrans has been achieved through the one‐pot condensation of aromatic aldehydes, malononitrile, and 4‐hydroxycoumarin, phenols or active methylene carbonyl compounds such as 1, 3‐cyclohexanedione and dimedone in the presence of 1‐butyl‐3‐methyl imidazolium hydroxide ([bmim]OH) as catalyst in aqueous media. This method offers several advantages short reaction time, high yields, and simple procedure. J. Heterocyclic Chem., (2009).