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Synthesis of Various Nitrogen Heterocycles as Antimicrobial Surface Agents
Author(s) -
ElSayed Refat,
Asghar Basim H.
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1918
Subject(s) - chemistry , antimicrobial , thiazole , stearic acid , 1,2,4 triazole , organic chemistry , triazole , propylene oxide , oxadiazole , combinatorial chemistry , ethylene oxide , copolymer , polymer
A number of novel, thiazole 5 , oxadiazole 6 , thiadiazole 7 , triazole 8 , 9 , and fused triazole derivatives 10 , 11 , 12 were obtained from a valuable and inexpensive fatty acids (stearic acid). Propoxylation of these compounds using 5 moles of propylene oxide produced nonionic surface active agents ( 13 , 14,15 16 , 17,18,19,20 ). The surface properties and the biodegradability of the latter compounds were evaluated. Some of the synthesized compounds were investigated for their antimicrobial activities.