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A Catalyst‐free Green Protocol for the Synthesis of Pyranopyrazoles Using Room Temperature Ionic Liquid Choline Chloride‐urea
Author(s) -
Swaroop Toreshettahally R.,
Sharath Kumar Kothanahally S.,
Palanivelu Mariyappan,
Chaitanya Somu,
Rangappa Kanchugarakoppal S.
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1864
Subject(s) - chemistry , ionic liquid , choline chloride , hydrazine (antidepressant) , urea , hydrate , catalysis , chloride , inorganic chemistry , choline , green chemistry , organic chemistry , chromatography , biochemistry
An efficient and rapid four component reaction of aldehydes, malanonitrile, β‐ketoesters and hydrazine hydrate (or phenyl hydrazine) in environmentally benign room temperature ionic liquid choline chloride‐urea has been developed for the synthesis of substituted 4 H ‐pyrano[2,3‐c]pyrazoles.