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Synthesis of 9‐amino‐5,6,7,8‐tetrahydrothieno[3,2‐ b ]quinoline and 9‐amino‐5,6,7,8‐tetrahydrothieno[3,2‐ b ]quinolin‐8‐ol derivatives
Author(s) -
Song YangHeon,
Jo Boung Sun
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.186
Subject(s) - chemistry , quinoline , cyclohexane , yield (engineering) , medicinal chemistry , stereochemistry , organic chemistry , metallurgy , materials science
The synthesis of 9‐amino‐5,6,7,8‐tetrahydrothieno[3,2‐ b ]quinoline ( 3 ) and 9‐amino‐5,6,7,8‐tetrahydrothieno[3,2‐ b ]quinolin‐5‐ol derivatives ( 4a , 4b , 4c , 4d , 4e , 4f , 4g ) in good yield by three‐step procedures starting from 3‐aminothiophene‐2‐carbonitrile and 5‐substituted cyclohexane‐1,3‐dione is described. J. Heterocyclic Chem., (2009).