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Efficient and Eco‐friendly Syntheses of 1,5‐Benzothiazepines and 1,5‐Benzodiazepines Catalyzed by [ Hmim ][NO 3 ] under Mild Conditions
Author(s) -
LoghmaniKhouzani Hossein,
Tamjidi Panteha,
MohammadpoorBaltork Iraj,
Yaeghoobi Marzieh,
Rahman Noorsaadah Abd.,
Khosropour Ahmad Reza,
Moghadam Majid,
Tangestaninejad Shahram,
Mirkhani Valiolah,
Habibi Mohammad Hossein,
Kashima Ayana,
Suzuki Takayoshi
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1827
Subject(s) - chemistry , diazepine , environmentally friendly , catalysis , ring (chemistry) , thiazine , combinatorial chemistry , medicinal chemistry , organic chemistry , ecology , biology
This article presents a synthetic method and reaction mechanism of the 1,5‐benzothiazepines and 1,5‐benzodiazepines derivatives. In this research, 36 thiazepines and diazepines (mostly new) with a new method have been prepared and their structures have been characterized by spectroscopic methods. Crystal structures of a new thiazepine and diazepine (seven‐membered rings) have also been determined and compared with thiazine (six‐membered ring). In this method, N ‐methylimidazolium nitrate [ Hmim ][NO 3 ] has been used as a catalyst that acts as an environmental friendly system.