Synthesis and Fungicidal Activity of ( E )‐α‐(Methoxyimino)benzeneacetate Derivatives Containing 1,2,4‐Triazole Schiff Base Side Chain

To find new strobilurin analogs with high activity against resistant pathogens, twelve ( E )‐α‐(methoxyimino)benzeneacetate derivatives containing 1,2,4‐triazole Schiff base side chain 3a , 3b , 3c , 3d , 3e , 3f , 3g , 3h , 3i , 3j , 3k , 3l were designed and synthesized. Their structures were confirmed by IR, 1 H‐NMR, EIMS, and elemental analyses. Bioassays indicated that most of the target compounds showed moderate to good fungicidal activities against Physalospora piricola Nose and Alternaria solani . For example, compounds 3d , 3e , and 3f possessed 99.5%, 100%, and 95.6% inhibition against Physalospora piricola Nose , whereas compounds 3d , 3f , and 3g exhibited 92%, 91%, and 92% inhibition against Alternaria solani at the concentration of 50 mg/L, respectively.