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One‐Pot Synthesis of 1,2,4,5‐Tetrasubstituted Imidazoles in Ionic Liquid
Author(s) -
Wan Yu,
Liu Guixiang,
Zhao Lingling,
Wang Haiying,
Huang Shuying,
Chen Liangfeng,
Wu Hui
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1751
Subject(s) - chemistry , benzil , aldehyde , ammonium acetate , ionic liquid , amine gas treating , condensation , ammonium , organic chemistry , ionic bonding , primary (astronomy) , catalysis , medicinal chemistry , ion , high performance liquid chromatography , physics , astronomy , thermodynamics
The four‐component condensation of benzil, aromatic aldehyde, primary amine, and ammonium acetate catalyzed by TFA in ionic liquid [Bpy]BF 4 at 80°C provided 1,2,4,5‐tetrasubstituted imidazoles in moderate to high yields.
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