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Tandem Aza‐Michael–Aldol Reactions: One‐Pot Synthesis of Functionalized Piperidine Derivatives
Author(s) -
Huang FuPing,
Dong ZhenWen,
Zhang HaiRui,
Hui XinPing
Publication year - 2014
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1750
Subject(s) - chemistry , piperidine , aldol reaction , tandem , michael reaction , cascade reaction , organic chemistry , combinatorial chemistry , stereochemistry , catalysis , materials science , composite material
A series of novel functionalized piperidine derivatives were conveniently prepared by three‐component tandem aza‐Michael–Aldol reactions of α,β‐unsaturated enones with substituted sulfonamides in the presence of DBU. The structures of the compounds synthesized were characterized by spectral data and X‐ray crystal diffraction.