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Synthesis of Pyrazole‐linked Norcantharidin Analogues of Substituted Chromones
Author(s) -
Wang Wei,
Deng Liping,
Tang Shenlong,
Qian Qing
Publication year - 2016
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1665
Subject(s) - chemistry , chromone , pyrazole , hydrazone , cycloaddition , ring (chemistry) , bicyclic molecule , triethylamine , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , catalysis
Eighteen novel pyrazole‐linked norcantharidin derivatives substituted by chromone ring were synthesized in a single step by the [3+2] 1,3‐dipolar cycloaddition reaction of norcantharidin derivatives of substituted aromatic amines with hydrazone in the presence of chloramine‐T as compared to the conventional method.