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Propargyl Anthranilate Derivatives and Their Application in the Synthesis of Rings Containing 1,2,3‐Triazolo Motifs
Author(s) -
Hradilová Ludmila,
Grepl Martin,
Hlaváč Jan,
Lyčka Antonín,
Hradil Pavel
Publication year - 2013
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1514
Subject(s) - chemistry , propargyl , intramolecular force , azide , intermolecular force , combinatorial chemistry , molecule , stereochemistry , organic synthesis , organic chemistry , catalysis
Propargyl anthranilate, a simple and less studied molecule with several reactive sites, is widely applicable in organic synthesis. An optimized synthesis of this compound and its derivatives and the preparation of azide derivatives are described. The optimized process of the known intramolecular cyclization is described, and the unknown intermolecular cyclizations of these azido derivatives and formation of a macrocycle are discussed.