New access to the one‐pot solvent‐free synthesis of 4,5‐dihydro‐pyrido[2,3‐ b ][1,4]diazepines and 2,3‐dihydro‐benzo[ b ][1,4]diazepines by microwave irradiation | Zendy

Goswami Shyamaprosad | Zendy; Hazra Anita | Zendy; Jana Subrata | Zendy

Premium

New access to the one‐pot solvent‐free synthesis of 4,5‐dihydro‐pyrido[2,3‐ b ][1,4]diazepines and 2,3‐dihydro‐benzo[ b ][1,4]diazepines by microwave irradiation

Author(s) -

Goswami Shyamaprosad,

Hazra Anita,

Jana Subrata

Publication year - 2009

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.148

Subject(s) - chemistry , aryl , solvent , catalysis , medicinal chemistry , organic chemistry , combinatorial chemistry , alkyl

A series of diversely substituted pyridodiazepines and benzodiazepines have been synthesized in solvent and catalyst free microwave condition from aryl/heteroaryl diamines and β‐aryl vinyl ketones. The yields of the reactions varied with the substituents attached to the aryl/heteroaryl diamines. This common protocol is equally effective for the synthesis of pyridodiazepines and benzodiazepines with pharmacological interest, though in case of pyridodiazepines required time is comparatively higher than benzodiazepines. J. Heterocyclic Chem., (2009).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research