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One‐pot three‐component synthesis of dihydrobenzo‐ and naphtho[ e ]‐1,3‐oxazines in water
Author(s) -
Mathew Bijoy P.,
Nath Mahendra
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.147
Subject(s) - chemistry , oxazines , condensation , aqueous solution , organic chemistry , component (thermodynamics) , aqueous medium , condensation reaction , combinatorial chemistry , catalysis , physics , thermodynamics
A simple, green and efficient method has been developed for the synthesis of biologically and materially important dihydrobenzo/naphtho[ e ]‐1,3‐oxazines in good to excellent yields through a Mannich‐type condensation cyclization reaction of aromatic alcohols with HCHO and primary amines in aqueous media at ambient temperature. J. Heterocyclic Chem., (2009).