Synthesis and Anticancer Activity of New Substituted Pyrazoles and Their Derived 1,2,4‐Triazoles and Sugar Derivatives | Zendy

Flefel Eman M. | Zendy; Tantawy Waled A. | Zendy; ElSayed Wael A. | Zendy; Sayed Hayam H. | Zendy; Fathy Nahed M. | Zendy

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Synthesis and Anticancer Activity of New Substituted Pyrazoles and Their Derived 1,2,4‐Triazoles and Sugar Derivatives

Author(s) -

Flefel Eman M.,

Tantawy Waled A.,

ElSayed Wael A.,

Sayed Hayam H.,

Fathy Nahed M.

Publication year - 2013

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.1122

Subject(s) - chemistry , thiazole , pyrazole , sugar , acetylation , triazole , combinatorial chemistry , organic chemistry , biochemistry , gene

New substituted pyrazole, thiazole, and 1,2,4‐triazole derivatives were synthesized. The sugar hydrazones, their acetylated derivatives as well as their derived acyclic C ‐nucleoside analogs, and the thioglycosides of the 1,2,4‐traizole derivatives were also prepared. The antitumor activity of some of the synthesized compounds were studied, and a number of the tested compounds showed significant activities.

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