Enaminone as  Building Blocks  in Organic Chemistry: A Novel Route to Polyfunctionally 2‐Substituted 5,6,7,8‐Tetrahydronaphthalenes and Their Antiviral Evaluation | Zendy

Hamdy Nehal A. | Zendy; ElSenousy Waled M. | Zendy; Fakhr Issa M. I. | Zendy

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Enaminone as Building Blocks in Organic Chemistry: A Novel Route to Polyfunctionally 2‐Substituted 5,6,7,8‐Tetrahydronaphthalenes and Their Antiviral Evaluation

Author(s) -

Hamdy Nehal A.,

ElSenousy Waled M.,

Fakhr Issa M. I.

Publication year - 2013

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.1080

Subject(s) - chemistry , benzimidazole , pyridine , hydrazone , reagent , pyrazole , benzene , combinatorial chemistry , organic chemistry , medicinal chemistry

The enaminone 2 reacts with different reagents to afford anilino, aroylpyridine, 1,3,5‐tri‐tetrahydronaphthoyl‐benzene, pyridine, 2,3,6‐trisubstituted pyridines, pyrazole, pyrido[1,2‐ a ]benzimidazole, and hydrazone derivatives 4 , 6 , 8 , 9 , 11 , 13 , 15 , 17 , 20 , and 21 . The antiviral evaluation of some selected new products showed promising antiviral activity against human adenovirus 7 and human rotavirus Wa strain.

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