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Synthesis of Bis Azole, Diazole, and Triazole Derivatives from N ‐(4‐Chloro/Iodophenyl)‐ N ‐carboxyethyl‐β‐alanine Dihydrazides
Author(s) -
Anusevicius Kazimieras,
Vaickelioniene Rita,
Mickevicius Vytautas,
Mikulskiene Gema
Publication year - 2013
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1070
Subject(s) - chemistry , azole , alanine , 1,2,4 triazole , nuclear magnetic resonance spectroscopy , elemental analysis , stereochemistry , proton nmr , carbon 13 nmr , medicinal chemistry , organic chemistry , antifungal , amino acid , medicine , biochemistry , dermatology
A new potentially biologically active N ‐(4‐chloro/iodophenyl)‐ N ‐carboxyethyl‐β‐alanine derivatives ( 2 , 2a , 2b , 3 , 3a , 3b , 4 , 4a , 4b , 8 , 8a , 8b , 9 , 9a , 9b ) and products of their cyclization 6 , 6a , 6b , 7 , 7a , 7b , 10 , 10a , 10b , 11 , 11a , 11b were obtained and characterized by the methods of 1 H‐NMR, 13 C‐NMR, IR, mass spectroscopy, and elemental analysis.