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A Facile Microwave‐Assisted “One‐Pot” Synthesis of Piperazino Pyrimidinyl Acetamides, a Class of Hybrid Bis Heterocycles and Their Structural Elucidation Using NMR Spectral Techniques
Author(s) -
Kanagarajan V.,
How Ghee Ang,
Siu Choon Ng,
Gopalakrishnan M.
Publication year - 2013
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.1046
Subject(s) - chemistry , heteronuclear single quantum coherence spectroscopy , microwave irradiation , catalysis , carbon 13 nmr , elemental analysis , microwave , melting point , proton nmr , combinatorial chemistry , nuclear chemistry , organic chemistry , nuclear magnetic resonance spectroscopy , physics , quantum mechanics
An array of novel piperazino pyrimidinyl acetamides, a class of hybrid bis heterocycles are synthesized in “ one‐pot ” by microwave irradiation method catalyzed by heterogeneous NaHSO 4 .SiO 2 catalyst in dry media and are characterized by melting point, elemental analysis, MS, FT‐IR, one‐dimensional NMR ( 1 H and 13 C) and two‐dimensional 1 H‐ 1 H COSY and 1 H‐ 13 C HSQC spectral data.