Synthesis of 8‐Oxoberbines and Related Benzolactams by Pd(OAc) 2 ‐Catalyzed Direct Aromatic  Carbonylation | Zendy

Miyazawa Mamoru | Zendy; Tokuhashi Takashi | Zendy; Horibata Akiyoshi | Zendy; Nakamura Takatoshi | Zendy; Onozaki Yu | Zendy; Kurono Nobuhito | Zendy; Senboku Hisanori | Zendy; Tokuda Masao | Zendy; Ohkuma Takeshi | Zendy; Orito Kazuhiko | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of 8‐Oxoberbines and Related Benzolactams by Pd(OAc) 2 ‐Catalyzed Direct Aromatic Carbonylation

Author(s) -

Miyazawa Mamoru,

Tokuhashi Takashi,

Horibata Akiyoshi,

Nakamura Takatoshi,

Onozaki Yu,

Kurono Nobuhito,

Senboku Hisanori,

Tokuda Masao,

Ohkuma Takeshi,

Orito Kazuhiko

Publication year - 2013

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.1044

Subject(s) - chemistry , carbonylation , catalysis , medicinal chemistry , selectivity , phosphine , palladium , alkoxy group , organic chemistry , carbon monoxide , alkyl

A variety of alkoxy‐substituted benzolactams with a berbine or yohimbane skeleton were prepared from 1‐benzyl‐1,2,3,4‐tetrahydroisoquinolines or 1‐benzyl‐1,2,3,4‐tetrahydro‐β‐carbolines by a phosphine‐free Pd(II)‐catalyzed direct aromatic carbonylation in a Pd(OAc) 2 ‐Cu(OAc) 2 catalytic system. The site selectivity was compared with that of the carbonylation with Pd(OAc) 2 or Pd(OAc) 2 ·2 PPh 3 , respectively.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research