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Validation of TG 13 severity grading in acute cholecystitis: Japan‐Taiwan collaborative study for acute cholecystitis
Author(s) -
Yokoe Masamichi,
Takada Tadahiro,
Hwang TsannLong,
Endo Itaru,
Akazawa Kohei,
Miura Fumihiko,
Mayumi Toshihiko,
Mori Rintaro,
Chen MiinFu,
Jan YiYin,
Ker ChenGuo,
Wang HsiuPo,
Itoi Takao,
Gomi Harumi,
Kiriyama Seiki,
Wada Keita,
Yamaue Hiroki,
Miyazaki Masaru,
Yamamoto Masakazu
Publication year - 2017
Publication title -
journal of hepato‐biliary‐pancreatic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 1868-6974
DOI - 10.1002/jhbp.457
Subject(s) - medicine , grading (engineering) , multicenter study , retrospective cohort study , mortality rate , acute cholecystitis , cholecystectomy , cholecystitis , histopathology , surgery , gastroenterology , gallbladder , pathology , civil engineering , engineering , randomized controlled trial
Background The collaborative multicenter retrospective study of acute cholecystitis ( AC ) was performed in Japan and Taiwan. The aim for this study was evaluation of the clinical value of TG 13 severity grading for AC . Method The study was designed as an international multicenter retrospective study of AC from 2011 to 2013. Based on the data, we investigated the TG 13 severity grading by analyzing the correlations between grade and prognosis, surgical procedures, histopathology, and organ dysfunction and prognosis. Results An investigation revealed that 30‐day overall mortality rate was 1.1% for Grade I, 0.8% for Grade II , 5.4% for Grade III . The mortality rate for Grade III was significantly higher than lower grades ( P < 0.001). The greater the number of organ dysfunction, the higher the mortality rate ( P < 0.001). However, the mortality rate varied depending on the number of organ dysfunction (3.1–25%). With respect to the surgical procedures, laparoscopic cholecystectomy was performed for Grade I patients ( P < 0.001), and the higher the grade, the more likely open surgery would be selected ( P < 0.001). Conclusion TG 13 severity grading criteria for AC are providing great benefits in actual clinical settings. From this study, the position of each severity grade was obviously confirmed.