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Long‐term outcomes after revision of Kasai portoenterostomy for biliary atresia
Author(s) -
Shirota Chiyoe,
Uchida Hiroo,
Ono Yasuyuki,
Murase Naruhiko,
Tainaka Takahisa,
Yokota Kazuki,
Oshima Kazuo,
Shirotsuki Ryo,
Hinoki Akinari,
Ando Hisami
Publication year - 2016
Publication title -
journal of hepato‐biliary‐pancreatic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 1868-6974
DOI - 10.1002/jhbp.395
Subject(s) - medicine , biliary atresia , liver transplantation , jaundice , retrospective cohort study , surgery , gastroenterology , transplantation
Background The indications for and efficacy of revision of portoenterostomy (PE) for biliary atresia (BA) needs to be reassessed in an era of liver transplantation. We therefore reviewed the long‐term outcomes following revision of PE. Methods This was a retrospective study of the medical records of patients with BA who underwent PE and revision of PE. We investigated the role of revision on outcomes of jaundice‐free native liver survival (approval number: 2015–0094). Results Portoenterostomy was performed in 76 patients, among whom 22 underwent revision. Revision for recurrent jaundice was performed for four of 51 patients, who were transiently jaundice free after initial PE, but only one achieved native liver survival. Revision for repeated cholangitis in two patients achieved native liver survival over 10 years. Revision was performed in 16 of the 25 patients in whom initial PE failed; of these, four survived with their native liver (ages 3, 12, 12, and 14 years). The PE revision did not significantly affect liver transplantation duration and survival outcome. Conclusions Revision of PE was suitable for repeated cholangitis. Revision for recurrent jaundice, regardless of whether the initial PE was successful, could have a limited but positive effect in preventing long‐term progressive liver failure.