Open AccessNo association between binge eating disorder and severity of non‐alcoholic fatty liver disease in severely obese patients
Author(s) -
Canivet Clémence M,
Perney Pascal,
Cherick Faredj,
Orlowski Magalie,
Patouraux Stéphanie,
BaillyMaitre Béatrice,
Tran Albert,
Iannelli Antonio,
Gual Philippe,
Anty Rodolphe
Publication year - 2020
Publication title -
jgh open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 8
ISSN - 2397-9070
DOI - 10.1002/jgh3.12309
Subject(s) - medicine , fatty liver , depression (economics) , anxiety , body mass index , binge eating disorder , hospital anxiety and depression scale , beck anxiety inventory , steatohepatitis , binge eating , beck depression inventory , physical therapy , obesity , gastroenterology , psychiatry , disease , bulimia nervosa , eating disorders , economics , macroeconomics
Background and Aim The main aim of this study was to evaluate if the binge eating disorders (BEDs) related to obesity were associated with the severity of non‐alcoholic fatty liver disease (NAFLD). Methods Severely obese patients who had been referred for bariatric surgery were included in this study at the Nice University Hospital. All patients underwent a liver biopsy at the time of surgery. Between 2008 and 2015, 388 patients had an assessable Bulimia Test (BULIT) self‐questionnaire at the time of surgery. A subgroup ( n = 183), between 2011 and 2015, also responded to a Beck Depression Inventory, Hospital Anxiety and Depression Scale, and a Fatigue Impact Scale autoquestionnaire. A control group of 29 healthy people matched by age and gender was included. Results Among the 388 obese patients (median age 40 years, body mass index 41.7 kg/m 2 , 81% women), 14 patients had a “probable diagnosis” of BED, and 47 patients had a “high risk” of developing a BED according to the BULIT. Obese patients had significantly more severe BED, depression, anxiety, and fatigue compared to controls. Steatosis, non‐alcoholic steatohepatitis, or fibrosis was not associated with BED. Similarly, the severity of NAFLD was not associated with depression, anxiety, or fatigue. Conclusions Severely obese patients had more severe BED, depression, anxiety, and fatigue than lean subjects independent of the severity of NAFLD.