Open AccessAsymptomatic pulmonary penicilliosis with a lung mass in an HIV‐infected patient
Author(s) -
Nishikubo Masashi,
Doi Asako,
Takegawa Hiroshi,
Yamashita Daisuke,
Ohira Junichiro,
Nishioka Hiroaki
Publication year - 2020
Publication title -
journal of general and family medicine
Language(s) - English
Resource type - Journals
ISSN - 2189-7948
DOI - 10.1002/jgf2.325
Subject(s) - medicine , asymptomatic , penicillium marneffei , itraconazole , bronchoalveolar lavage , lung , respiratory system , differential diagnosis , human immunodeficiency virus (hiv) , pathology , dermatology , immunology , coinfection , antifungal
Abstract Penicillium marneffei ( Talaromyces marneffei ) infection sometimes occurs in HIV‐infected patients in South‐East Asia. However, reports on asymptomatic cases are rare. Herein, we report a case of a 27‐year‐old Burmese HIV‐positive woman with pulmonary penicilliosis. Chest radiography showed a lung mass; however, the patient did not have any respiratory symptoms. Cultures of bronchoalveolar lavage and lung tissue grew P marneffei . The patient was diagnosed with penicilliosis and successfully treated with amphotericin B and itraconazole. Our findings suggest that P marneffei infection should be considered in the differential diagnosis of a lung mass in HIV‐infected patients, even when asymptomatic for respiratory symptoms.