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Contribution of the tooth bud mesenchyme to alveolar bone
Author(s) -
Diep Lisa,
Matalova Eva,
Mitsiadis Thimios A.,
Tucker Abigail S.
Publication year - 2009
Publication title -
journal of experimental zoology part b: molecular and developmental evolution
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 63
eISSN - 1552-5015
pISSN - 1552-5007
DOI - 10.1002/jez.b.21269
Subject(s) - dental papilla , mesenchyme , dental follicle , dental alveolus , periodontium , mesenchymal stem cell , enamel organ , dentistry , biology , anatomy , microbiology and biotechnology , medicine , dentin , ameloblast , enamel paint , odontoblast
This study highlights the dynamic nature of the mesenchymal cells during tooth development from the bud to the bell stage. Condensing mesenchymal cells, labelled on either side of the developing tooth bud, move toward the presumptive roots forming an arc of cells under the dental papilla. These labelled cells take part in formation of the dental follicle, which contributes to both the tooth and its surrounding periodontium, including the supporting alveolar bone. This study, thus, physically links development of the tooth with the tissue into which it develops. The results obtained clearly indicate that the tooth organ is an entity comprising dental and periodontal tissue. J. Exp. Zool. (Mol. Dev. Evol.) 312B:510–517, 2009 . © 2009 Wiley‐Liss, Inc.