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Evaluation of the effects of silver nanoparticles on Danio rerio cornea: Morphological and ultrastructural analysis
Author(s) -
Pecoraro Roberta,
Salvaggio Antonio,
Scalisi Elena M.,
Iaria Carmelo,
Lanteri Giovanni,
Copat Chiara,
Ferrante Margherita,
Fragalà Giuseppe,
Zimbone Massimo,
Impellizzeri Giuliana,
Brundo Maria V.
Publication year - 2019
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.23280
Subject(s) - silver nanoparticle , danio , ultrastructure , chemistry , zebrafish , cornea , corneal epithelium , nanoparticle , epithelium , anatomy , pathology , nanotechnology , biology , materials science , ophthalmology , medicine , biochemistry , gene
Abstract Although in recent years there has been intensification in the use of nanoparticles (NPs) for the production of many commercial products, few studies have been carried out to assess the risks associated with its use. Among the most used NPs, silver nanoparticles (AgNPs) have a preponderant position as they have various applications. In this study, 40 adult zebrafish were exposed to increasing concentrations of AgNPs (8, 45, and 70 μg/L) for 30 days to evaluate the effects on eyes after chronic exposure to AgNPs with an average diameter of 50 nm. From the morphological and ultrastructural analysis performed, no alteration or lesions of the corneal epithelium were detected.