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Synthesis, characterization and use of iron oxide nano particles for antibacterial activity
Author(s) -
Saqib Saddam,
Munis Muhammad Farooq Hussain,
Zaman Wajid,
Ullah Fazal,
Shah Syed Nasar,
Ayaz Asma,
Farooq Muhammad,
Bahadur Saraj
Publication year - 2019
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.23182
Subject(s) - antibacterial activity , nanoparticle , bacteria , iron oxide nanoparticles , biocompatibility , chemistry , iron oxide , nuclear chemistry , nanotechnology , scanning electron microscope , escherichia coli , characterization (materials science) , precipitation , chemical engineering , materials science , biochemistry , biology , organic chemistry , genetics , physics , meteorology , gene , engineering , composite material
In this decade, the use of nano particles (NPs) against bacterial growth is increasing day by day due to remarkable alternative properties compared to molecular antibiotics. Thus, the use of iron oxide nanoparticles (IONPs) has proven one of the most important transition metals oxide‐based remedy in nanotechnological advances and biological applications due to enriched biocompatibility of iron. In this study synthesis of IONPs was carried out via co‐precipitation method. The crystallographic morphology of the synthesized particles was studied via X‐ray diffraction which revealed cubic structure of the particles, whereas, the spinal shaped morphology of the prepared NPs was confirmed from scanning electron microscopy. Likewise, the presence of the major elements in the sample was determined through energy dispersive X‐ray analysis characterization. Bactericidal effect of the NPs was assessed at pre‐defined concentrations (50 and 100 μg/ml) against Gram +ve bacteria Staphylococcus aureus, Gram −ve bacteria Shigella dysentry and Escherichia coli . Bacterial strains, which demonstrate the potential of NPs. The purpose of this study was assessing the structure of the synthesized NPs for protective effect against harmful bacterial activity.

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