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Investigation of mineral content of root canal dentin after the application of various antibiotic paste using energy‐dispersive X‐ray detector
Author(s) -
Simsek H.,
Coruh M.,
Cakici F.,
Fundaoglu Kucukekenci F.,
Gurbuz T.,
Cakici E. B.
Publication year - 2019
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.23155
Subject(s) - root canal , cefaclor , dentistry , dentin , amoxicillin , minocycline , nuclear chemistry , chemistry , materials science , antibiotics , medicine , biochemistry , cephalosporin
The purpose of this study was to evaluate mineral content of root canal dentin after treatment with different antibiotic pastes including the mixture of metronidazole, ciprofloxacin, doxycycline, cefaclor, amoxicillin, or minocycline. Fifty extracted maxillary canine teeth were randomly divided into five groups ( n = 10 teeth for each group). Root canals were prepared Reciproc rotary files. Canals were irrigated using 5 ml 5% NaOCl and 1 ml 15% EDTA. Each tooth in all groups were longitudinally splitted into two pieces as a control and experimental samples. Each experimental group received following antibiotic paste; double antibiotic paste (DAP) and triple antibiotic paste with doxycycline (TAPd), TAP with cefaclor (TAPc), TAP with amoxicillin (TAPa), and TAP with minocycline (TAPm) for 21 days. The Ca, P, Mg, Ca, and K levels, and the Ca/P ratio was analyzed by a scanning electron microscope (SEM) equipped using a Bruker energy‐dispersive X‐Ray (EDX) detector. Data were analyzed with independent samples t ‐test, one‐way anova, and Duncan tests. Ca and Ca/P ratio showed a statistically significant increase TAP with amoxicillin and cefaclor ( p < .05). DAP, TAPd, and TAPm did not change the mineral levels ( p > .05). TAPa and TAPc with increased the Ca level and Ca/P ratio of the root canal dentin which consequently positively influences the revascularization process.