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Mapping of somatostatin‐28 (1‐12) in the alpaca ( L ama pacos ) brainstem
Author(s) -
De Souza Eliana,
Sánchez Manuel Lisardo,
Aguilar Luís Ángel,
DíazCabiale Zaida,
Narváez José Ángel,
Coveñas Rafael
Publication year - 2015
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.22482
Subject(s) - brainstem , dorsal motor nucleus , pons , superior colliculus , anatomy , medulla oblongata , nucleus , reticular formation , hypoglossal nucleus , parabrachial nucleus , inferior colliculus , tegmentum , midbrain , chemistry , neuroscience , biology , vagus nerve , central nervous system , stimulation
Using an indirect immunoperoxidase technique, we studied the distribution of cell bodies and fibers containing somatostatin‐28 (1‐12) in the alpaca brainstem. Immunoreactive fibers were widely distributed throughout the whole brainstem: 34 brainstem nuclei/regions showed a high or a moderate density of these fibers. Perikarya containing the peptide were widely distributed throughout the mesencephalon, pons and medulla oblongata. Cell bodies containing somatostatin‐28 (1‐12) were observed in the lateral and medial divisions of the marginal nucleus of the brachium conjunctivum, reticular formation (mesencephalon, pons and medulla oblongata), inferior colliculus, periaqueductal gray, superior colliculus, pericentral division of the dorsal tegmental nucleus, interpeduncular nucleus, nucleus of the trapezoid body, vestibular nucleus, motor dorsal nucleus of the vagus, nucleus of the solitary tract, nucleus praepositus hypoglossi, and in the substantia nigra. This widespread distribution indicates that somatostatin‐28 (1‐12) is involved in multiple physiological actions in the alpaca brainstem. Microsc. Res. Tech. 78:363–374, 2015 . © 2015 Wiley Periodicals, Inc.