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Response of mice connective tissue to three different endodontic materials
Author(s) -
Kurita Lucio Mitsuo,
Cavalcante Roberta Barroso,
GurgelFilho Eduardo Diogo,
DeDeus Gustavo André,
Ximenes Ana Beatriz,
Silva Emmanuel João Nogueira Leal
Publication year - 2013
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.22168
Subject(s) - mineral trioxide aggregate , granulation tissue , connective tissue , biocompatibility , h&e stain , subcutaneous tissue , capsule , granulation , dentistry , pathology , medicine , materials science , staining , wound healing , biology , surgery , composite material , botany , metallurgy
The aim of this study was to evaluate the biocompatibility of mineral trioxide aggregate ( MTA ) Bio and Portland cement ( PC ) and compare with those of ProRoot MTA . Polyethylene tubes were filled with materials and placed into dorsal subcutaneous connective tissue of Wistar albino rats. After 7, 30, and 60 days after the surgical procedure, the implants with the surrounding tissue were removed. Tissue samples were subjected to histological processing, and sections were stained with hematoxylin and eosin. Sections were evaluated for the intensity of inflammation, predominant cell type, presence of fibrous capsule and granulation tissue. Data were submitted to Kruskal‐Wallis test at a significant level of P ≤ 0.05. No statistical differences were observed at any evaluated condition among tested materials ( P > 0.05). Statistically significant differences were observed between mean inflammatory scores, cell types and granulation tissue of the same material in different experimental periods ( P < 0.05). Can be concluded that biocompatibility of MTA bio and PC were comparable with that of ProRoot MTA . Microsc. Res. Tech. 76:311–315, 2013 . © 2013 Wiley Periodicals, Inc.