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Distribution and regulation of substance P‐related peptide in the frog visual system
Author(s) -
Debski Elizabeth A.
Publication year - 2001
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.1134
Subject(s) - amphibian , leopard frog , neuropeptide , biology , substance p , neuroscience , rana , function (biology) , peptide , microbiology and biotechnology , anatomy , receptor , ecology , biochemistry
Abstract Modulation of visual signal activity has consequences for both signal processing and for activity‐dependent structuring mechanisms. Among the neuromodulatory agents found in visual areas are substance P (SP)‐related peptides. This article reviews what is known about these substances in the amphibian retina and optic tectum with special emphasis on the leopard frog, Rana pipiens . It is found that the distribution of these SP‐related peptides is remarkably similar to that seen in mammals. This suggests that study of model amphibian systems may significantly enhance our understanding of how neuropeptides contribute to visual system function and organization. Microsc. Res. Tech. 54:220–228, 2001. © 2001 Wiley‐Liss, Inc.