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Gastric leptin
Author(s) -
Lewin Miguel J.M.,
Bado André
Publication year - 2001
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.1105
Subject(s) - leptin , gastrin , cholecystokinin , somatostatin , cytoprotection , hormone , enteroendocrine cell , exocrine pancreas , gastric mucosa , secretion , biology , medicine , endocrinology , pancreas , stomach , endocrine system , obesity , oxidative stress , receptor
The recent discovery of gastric leptin has initiated several investigations on the possible role of leptin in digestive physiology. The following clues are currently suggested: leptin might control meal size in cooperation with Cholecystokinin, help cytoprotection of the gastric mucosa, play a role in gut inflammatory processes, regulate secretion of gastric hormones such as gastrin and somatostatin, and modulate intestinal transport of small peptides. The present review is a brief survey of the most significant advances in these issues. Microsc. Res. Tech. 53:372–376, 2001. © 2001 Wiley‐Liss, Inc.