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Nucleic acid compartmentalization within the cell nucleus by in situ transferase‐immunogold techniques
Author(s) -
Thiry M.
Publication year - 1995
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.1070310103
Subject(s) - immunogold labelling , compartmentalization (fire protection) , nucleus , cell nucleus , nucleic acid , ultrastructure , in situ , microbiology and biotechnology , biology , cell , dna , rna , nucleolus , precursor mrna , chemistry , biochemistry , anatomy , rna splicing , enzyme , gene , organic chemistry
In the present review, we report on recent results obtained by in situ transferaseimmunogold techniques as to the ultrastructural distribution of DNA and RNA within the cell nucleus. Special emphasis is placed on the various nucleolar components and the various enigmatic structures of the extranucleolar region: interchromatin granules, coiled bodies, and simple nuclear bodies. These data are discussed in the light of our current understanding of the functional organization of the cell nucleus. © 1995 Wiley‐Liss, Inc.