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Pathological examination of sentinel lymph node in breast cancer: Potential problems and possible solutions
Author(s) -
Hoda Syed A.,
Chiu April,
Resetkova Erika,
Harigopal Malini,
Hoda Rana S.,
Osborne Michael P.
Publication year - 2002
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/jemt.10179
Subject(s) - sentinel lymph node , axilla , medicine , breast cancer , biopsy , axillary lymph node dissection , pathological , lymph node , breast carcinoma , pathology , cancer , radiology
Sentinel lymph node (SLN) biopsy has emerged during the last few years as a viable option for staging the axilla in the treatment of breast carcinoma. This procedure can potentially identify patients who would be helped by full axillary lymph node dissection (the SLN‐positive cases), and those who would not (the SLN‐negative cases). Review of the literature confirms the promise of SLN; however, the possible problems in the pathological handling of SLN, including the microscopic misinterpretation of benign structures and “spurious” immunohistochemical staining, need wider recognition. Microsc. Res. Tech. 59:85–91, 2002. © 2002 Wiley‐Liss, Inc.