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Cortical motor areas show different reorganizational changes in adult patients with brachial plexus birth injury (BPBI)
Author(s) -
Tuna Zeynep,
Oskay Deran,
Algin Oktay,
Koçak Orhan Murat
Publication year - 2020
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1002/jdn.10037
Subject(s) - neuroplasticity , brachial plexus , inferior parietal lobule , supplementary motor area , functional magnetic resonance imaging , brachial plexus injury , neuroscience , magnetic resonance imaging , superior parietal lobule , medicine , primary motor cortex , psychology , motor cortex , anatomy , stimulation , radiology
Abstract Introduction Brachial plexus birth injury (BPBI) may cause permanent disability. It is recently thought to result from the (mal)adaptive reorganizational central nervous system problems. Methods In this study, adult patients with BPBI and age‐matched healthy controls were compared for the cortical activity during action observation by functional magnetic resonance imaging (fMRI). Results The cortical activity in patients was significantly weaker than in the control group ( p < .05). Areas of difference were middle temporal gyrus, premotor area, and inferior parietal lobule. The signal change in these areas was significantly lower in the patient group ( p < .05). Conclusions This study showed that the cortical activity in the associative motor regions was weaker in the patients while no primary region showed any difference. The results were concluded that there is a diversity in the neuroplastic changes between primary and associative motor areas. Clinically, neurorehabilitative interventions should be planned based on this diversity.