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Assessment of atrial functional remodeling in patients with atrioventricular nodal reentrant tachycardia with and without drug‐induced type 1 Brugada pattern: A case‐control study
Author(s) -
Kocabaş Umut,
Payzın Serdar,
Hasdemir Can
Publication year - 2021
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22990
Subject(s) - medicine , tachycardia , pr interval , cardiology , atrioventricular node , doppler imaging , electrocardiography , population , heart rate , blood pressure , diastole , environmental health
Purpose The time interval between the onset of the P‐wave on electrocardiogram (ECG) and peak A′ velocity of the lateral left atrial wall assessed by tissue Doppler imaging (PA‐TDI interval) determine total atrial conduction time (TACT) which reflects atrial remodeling and arrhythmic substrate. In this retrospective study, we aimed to assess TACT in patients with atrioventricular nodal reentrant tachycardia (AVNRT) with and without drug‐induced type 1 Brugada electrocardiogram ECG pattern (DI‐Type 1 BrP) and control subjects. Methods Study population consisted of 62 consecutive patients (46 women; mean age 44 ± 12 years) undergoing electrophysiological study and ablation for symptomatic, drug‐resistant AVNRT, and 42 age‐matched and sex‐matched control subjects. All patients and control subjects underwent ajmaline challenge test and tissue Doppler imaging. Results A DI‐Type 1 BrP was uncovered in 24 of 62 patients with AVNRT (38.7%). PA‐TDI interval was similar among AVNRT patients with and without DI‐Type 1 BrP (124 ± 12 ms vs 119 ± 14 ms, respectively, P = .32), but significantly longer in patients with AVNRT with as well as without DI‐Type 1 BrP than in control subjects (124 ± 12 ms and 119 ± 14 ms vs 105 ± 11 ms, respectively, P < .001). Conclusion The TACT assessed by PA‐TDI interval is longer in patients with AVNRT with and without DI‐Type 1 BrP than in age‐matched and sex‐matched healthy control subjects.