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Prenatal diagnosis of middle interhemispheric variant of holoprosencephaly: Report of two cases
Author(s) -
Zantow Emily,
Bryant Stefanie,
Pierce Stephanie L,
DuBois Molly,
Maxted Marta,
Porter Blake
Publication year - 2021
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22984
Subject(s) - holoprosencephaly , medicine , septum pellucidum , abnormality , lateral ventricles , anatomy , fetus , pregnancy , biology , genetics , psychiatry
Holoprosencephaly ranges in severity based on the degree of anatomic abnormality. Middle interhemispheric variant of holoprosencephaly is a less common and often milder variant that has the characteristic sonographic findings of an absent cavum septum pellucidum and a single fused ventricle. This subtype may be associated with genetic conditions that have not been well‐described in the literature. We present two cases of middle interhemispheric variant of holoprosencephaly diagnosed on fetal ultrasound.