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Performance of a local reference curve for predicting small for gestational age fetuses in pregnant women with HIV / AIDS
Author(s) -
Kato Daniel Massamatsu Pianovski,
Lorusso Liziane,
Bruns Rafael Frederico,
Pinhat Elisa Chicareli,
Dalla Costa Natália Roberta Andrade,
Pletsch Letícia,
Araujo Júnior Edward
Publication year - 2021
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22961
Subject(s) - medicine , receiver operating characteristic , small for gestational age , area under the curve , gold standard (test) , fetus , gestational age , obstetrics , population , kappa , human immunodeficiency virus (hiv) , pregnancy , mathematics , immunology , geometry , environmental health , biology , genetics
Purpose To compare the performance of a local estimated fetal weight curve with curves established for other populations to predict small for gestational age (SGA) fetuses. Methods A retrospective and cross‐sectional study involving 231 fetuses in which the performance of a local curve (proposed model) was compared with the Hadlock and Intergrowth‐21st curves in the prediction of SGA fetuses, by applying them to a population of high‐risk pregnant woman with HIV/AIDS. For each model, a receiver operating characteristic curve was adjusted, considering the SGA classification by the neonatal Intergrowth method as the gold standard, and the area under the curve (AUC) was calculated. Results The models presented linear correlations with each other. The agreement of the proposed model with Hadlock was very good (kappa = 0.83), whereas the proposed model and Intergrowth‐21st had moderate agreement (kappa = 0.44). The SGA fetus detection sensitivities of the proposed model and Hadlock were 61.9% and 57.1%, with specificity of 84.1% and 86.2% and accuracy of 80.1% and 81%, respectively, without statistical difference. The sensitivity of the Intergrowth‐21st model was 33.3%, while the accuracy was 85.7% and the specificity was 97.4%. The AUC estimated values for the Hadlock, proposed, and Intergrowth‐21st models were 0.834, 0.832, and 0.835, respectively. Conclusion The proposed model and Hadlock were interchangeable in the prediction of SGA fetuses and superior to the Intergrowth‐21st model.