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Middle cerebral artery peak systolic velocity in perinatal cytomegalovirus infection
Author(s) -
Duncan Jose R.,
Sche Mauro H.,
Argoti Pedro S.,
Mari Giancarlo
Publication year - 2019
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22715
Subject(s) - medicine , middle cerebral artery , anemia , fetus , human cytomegalovirus , cytomegalovirus , pathophysiology , cardiology , population , pregnancy , viral disease , immunology , herpesviridae , virus , environmental health , ischemia , biology , genetics
Abstract A middle cerebral artery peak systolic velocity value (MCA‐PSV) persistently greater than 1.5 times the median of the normal population is utilized to detect moderate and severe anemia in fetuses at risk. Cytomegalovirus (CMV) is the most common perinatal infection and can cause fetal anemia. We present four cases with CMV perinatal infection. Although their MCA‐PSV values were the highest recorded in normal as well as in anemic fetuses, only two of them developed moderate or severe anemia. These findings suggest that high MCA‐PSV values in cases with perinatal CMV infection may have a different pathophysiologic mechanism than anemia.