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Regression equations for calculation of z scores for echocardiographic measurements of left heart structures in healthy Han Chinese children
Author(s) -
Wang ShanShan,
Hong WenJing,
Zhang YuQi,
Chen ShuBao,
Huang GuoYing,
Zhang HongYan,
Chen LiJun,
Wu LanPing,
Shen Rong,
Liu YiQing,
Zhu JunXue
Publication year - 2018
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22579
Subject(s) - medicine , cardiology , ejection fraction , interventricular septum , diastole , heart disease , heart failure , blood pressure , ventricle
Objective Clinical decision making in children with heart disease relies on detailed measurements of cardiac structures using two‐dimensional and M‐mode echocardiography. However, no echocardiographic reference values are available for the Chinese children. We aimed to establish z‐score regression equations for left heart structures in a population‐based cohort of healthy Chinese Han children. Method Echocardiography was performed in 545 children with a normal heart. The dimensions of the aortic valve annulus (AVA), aortic sinuses of Valsalva (ASV), sinotubular junction (STJ), ascending aorta (AAO), left atrium (LA), mitral valve annulus (MVA), interventricular septal end‐diastolic thickness (IVSd), interventricular septal end‐systolic thickness (IVSs), left ventricular end‐diastolic diameter (LVIDd), left ventricular end‐systolic diameter (LVIDs), left ventricular posterior wall end‐diastolic thickness (LVPWd), left ventricular posterior wall end‐systolic thickness (LVPWs) were measured. Regression analyses were conducted to relate the measurements of left heart structures to body surface area (BSA). Left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were calculated. Several models were used, and the adjusted R2 values were compared for each model. Results AVA, ASV, STJ, AAO, LA, MVA, IVSd, IVSs, LVIDd, LVIDs, LVPWd, and LVPWs had a cubic relationship with BSA. LVEF and LVFS fell within a narrow range. Conclusions Our results provide reference values for z scores and regression equations for left heart structures in Han Chinese children. These data may help make a quick and accurate judgment of the routine clinical measurement of left heart structures in children with heart disease.