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Ultrasound‐guided core needle biopsy of cervical lymph nodes in the diagnosis of toxoplasmosis
Author(s) -
Cho Woojin,
Kim Min Kyung,
Sim Jung Suk
Publication year - 2017
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22431
Subject(s) - medicine , follicular hyperplasia , lymph node , biopsy , lymph , ultrasound , lymph node biopsy , toxoplasmosis , radiology , pathology , cervical lymph nodes , metastasis , cancer
ABSTRACT Background Our study investigates whether the histopathological features of toxoplasmic lymphadenitis (TL), specifically noncaseating microgranuloma and follicular hyperplasia, can be obtained by sonographic‐guided core needle biopsy (CNB) of cervical lymph nodes. Methods Thirty‐two patients seen from June 2014 to March 2015 were positive for toxoplasma immunoglobulin M antibody. Among those patients, 21 underwent CNB of a cervical lymph node and were enrolled in this study. The pathologic findings were reviewed. Results Twenty‐nine lymph nodes in 21 patients were sampled. Eighteen of the 21 (86%) patients had a microgranuloma without caseating necrosis or giant cells, and all 21 (100%) patients had follicular hyperplasia. Conclusions The histologic findings of TL were detected by sonographic‐guided CNB, which can be used as part of the first line of investigation in patients with unexplained cervical adenopathy. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45 :192–196, 2017;