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Prenatal features of Pena‐Shokeir sequence with atypical response to acoustic stimulation
Author(s) -
Pittyat Sirida,
Jatavan Phudit,
Suwansirikul Songkiat,
Tongsong Theera
Publication year - 2016
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22373
Subject(s) - medicine , polyhydramnios , fetus , fetal movement , stimulation , ultrasound , breathing , heart rate , anatomy , pregnancy , radiology , blood pressure , genetics , biology
A fetal sonographic screening examination performed at 23 weeks showed polyhydramnios, micrognathia, fixed postures of all long bones, but no movement and no breathing. The fetus showed fetal heart rate acceleration but no movement when acoustic stimulation was applied with artificial larynx. All these findings persisted on serial examinations. The neonate was stillborn at 37 weeks and a final diagnosis of Pena‐Shokeir sequence was made. In addition to typical sonographic features of Pena‐Shokeir sequence, fetal heart rate accelerations with no movement in response to acoustic stimulation suggests that peripheral myopathy may possibly play an important role in the pathogenesis of the disease. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44 :459–462, 2016;