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Gray‐scale and color Doppler sonographic features of complex fibroadenomas of the breast
Author(s) -
Lee Kwang Hwi,
Kim Suk Jung,
Park Young Mi,
Kim Woogyeong,
Yoon Jung Hee,
Song Jong Woon,
Kim Seung Ho,
Lim YunJung,
Baek Hye Jin,
Kim SeonJeong,
Lee Yedaun
Publication year - 2015
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22278
Subject(s) - medicine , vascularity , fibroadenoma , echogenicity , bi rads , confidence interval , odds ratio , breast fibroadenoma , radiology , ultrasound , pathology , mammography , breast cancer , cancer
Purpose To investigate gray‐scale and color Doppler sonographic (US) features of complex fibroadenoma (FA), according to the Breast Imaging‐Reporting and Data System (BI‐RADS) lexicon. Methods From 2010 through 2013, 586 women with FAs were seen; 101 (17%) of those lesions were diagnosed as complex FAs on percutaneous needle biopsy or surgery. Among the patients with complex FAs, 67 who had US examination results available were included in this study. In addition, the results from 98 women who had simple FAs were included as controls. US features were retrospectively analyzed by two breast radiologists in consensus for shape, margin, echogenicity, posterior acoustic pattern, boundary, orientation, and associated findings. They also reassessed the BI‐RADS category for FAs. Color Doppler US examination results were classified according to the amount of vascularity as absent, moderate, or marked. Results Complex FA were larger than simple FAs were (14.5 cm versus 12.1 cm, p > 0.05). On univariate analysis, a round to irregular shape, an uncircumscribed margin, the presence of associated findings, and BI‐RADS categorization as 4a and 4b were more frequently revealed in complex than in simple FAs ( p < 0.05). Multivariate analysis revealed that the tumor margin was a predictive factor for complex FA (odds ratio: 6.08; 95% confidence interval: 1.14–32.49, p < 0.05). On color Doppler US, the complex FAs had higher degrees of vascularity than simple FA ( p < 0.05). Conclusions Complex FAs, in comparison with simple FAs, tend to have more aggressive features and to be in higher BI‐RADS categories on US examination. © 2015 Wiley Periodicals, Inc. J Clin Ultrasound 43 :556–562, 2015